Free Udemy Course: Diploma in Genomics and Genetic Engineering

DescriptionTake the next step in your scientific journey! Whether you're an aspiring researcher, a budding biotechnologist, a healthcare professional, or simply passionate about exploring the vast potential of genomics and genetic engineering, this course is your gateway to mastering the principles of genome science and genetic modification. Strengthen your knowledge of DNA sequencing, regulation of gene expression, and genome editing technologies like CRISPR-Cas9, enhance your analytic skills in molecular techniques, and build a solid foundation for advancements in personalized medicine, biotechnology, and genetic research. This is your opportunity to elevate your expertise, drive scientific innovation, and make a meaningful impact in the ever-evolving fields of genomics and genetic engineering!With this course as your guide, you learn how to:· Understand the fundamental concepts and principles of genomics and genetic engineering.· Explore the structure, function, and regulation of genes and genomes, along with their role in biological systems.· Gain insights into key genomic techniques such as CRISPR-Cas9 genome editing, next-generation sequencing (NGS), and recombinant DNA technology.· Learn about the applications of genomics and genetic engineering in fields like biotechnology, personalized medicine, agriculture, and synthetic biology.· Invest in your knowledge today and build a strong foundation for advanced studies and groundbreaking research in genomics, bioinformatics, and genetic engineering.The Frameworks of the CourseEngaging video lectures, case studies, assessments, downloadable resources, and interactive exercises form the foundation of this course. This course is designed to provide an in-depth understanding of genomics and genetic engineering, their significance, and applications through various chapters and units.You will explore key concepts such as genome structure, regulation of gene expression, and genetic variation, along with fundamental processes like DNA sequencing, transcriptional regulation, and genome editing. The course will cover topics including mutations, DNA repair, proteomics, epigenetics, and CRISPR-based gene editing technologies.The course will also introduce essential laboratory techniques such as next-generation sequencing (NGS), polymerase chain reaction (PCR), recombinant DNA technology, and gene cloning, enhancing your practical understanding of genome analysis and manipulation.This course also helps you to strengthen your knowledge and application of genomics and genetic engineering preparing you for advanced research and innovation in these cutting-edge domains.In the first part of the course, you’ll learn about introduction, scopes and applications of Genomics. You will learn about genome organization. You will learn the details about epigenetics. You will also understand about mutations and DNA repair mechanisms. You will also know about Proteomics and Translation process and also post-translational modification processes.In the middle part of the course, you’ll be able to learn about regulation of gene expression. You will learn the details about transcriptional, post-transcriptional, translational, post-translational regulation. You will also learn about epigenetic regulation, microRNA and long non-coding RNA regulation. You will also learn about genomic technologies. You will have the knowledge on DNA sequencing. Understand Sanger sequencing method. You will also learn about Next Generation sequencing and key methods of next generation sequencing. You will learn about applications of DNA sequencing.In the final part of the course, you’ll learn about Genetic Engineering. You will have knowledge on Recombinant DNA Technology, DNA cloning, Polymerase Chain Reaction and Gene editing (CRISPR-Cas 9) process.Course Content:Part 1Introduction and Study Plan· Introduction and know your instructor· Study Plan and Structure of the CourseModule 1: Genomics1.1. Introduction on Genomics.1.2. Comparison between Genomics and Genetics.1.3. Timeline of major milestones in genomics.1.4. Human Genome Project.1.5. Introduction on Types of Genomics.1.6. Scopes of Genomics.1.7. Applications of Genomics.Module 2: Genome Organization.2.1 Comparison between prokaryotic and eukaryotic genome organization.2.2 Non-Coding DNA.2.3 Repetitive Elements.2.4 Introduction to Epigenetics.2.5 Key concepts and mechanisms in epigenetics- DNA Methylation, Histone Modifications, Non-Coding RNAs.2.6 Key concepts and mechanisms in epigenetics-Epigenetic Inheritance.2.7 Key concepts and mechanisms in epigenetics- X-Chromosome Inactivation.Module 3: Mutations and DNA Repair Mechanisms.3.1 Introduction on Mutations and DNA Repair Mechanisms.3.2 Causes of Mutations-Comparison between Spontaneous and Induced Mutation.3.3 Mutagens.3.4 Spontaneous Mutations and Causes of Spontaneous Mutations.3.5 Spontaneous Mutations -Replication Errors.3.6 Spontaneous Mutations -Tautomeric Shifts.3.7 Spontaneous Mutations -Deamination.3.8 Spontaneous Mutations -Depurination.3.9 Types of Mutations -Point Mutations.3.10 Types of Mutations - Frameshift Mutations.3.11 Types of Mutations - Nucleotide Repeat Expansion Mutations.3.12 Types of Mutations - Chromosomal Aberrations Mutations.3.13 DNA Repair Mechanisms.3.14 DNA Repair Mechanisms- Direct Reversal Repair (Photoreactivation Repair).3.15 DNA Repair Mechanisms-Base Excision Repair (BER).3.16 DNA Repair Mechanisms- Nucleotide Excision Repair (NER).3.17 DNA Repair Mechanisms- Mismatch Repair (MMR).3.18 DNA Repair Mechanisms-Double Strand Break Repair (Homologous recombination and Non-Homologous End Joining).3.19 DNA Repair Mechanisms-Translesion Synthesis (TLS).3.20 DNA Repair Mechanisms-Cross-link Repair.Module 4: Proteomics4.1 Introduction to Proteomics.4.2 Key Aspects and Types of Proteomics.4.3 Interactions between Genomics and Proteomics.4.4 Introduction to Protein Synthesis in Proteomics.4.5 Role of Ribosomes in Protein Synthesis.4.6 Transfer RNA (tRNA).4.7 Aminoacyl-tRNA Synthetases.4.8 The Universal Genetic Code.4.9 Codons and Anticodons.4.10 Wobble Hypothesis4.11 Translation process- Initiation.4.12 Translation process- Elongation.4.13 Translation process- Termination.4.14 Post-Translational Modifications.4.15 Post-Translational Modifications- Phosphorylation Process.4.16 Post-Translational Modifications-Glycosylation Process.4.17 Post-Translational Modifications-Acetylation Process.4.18 Post-Translational Modifications- Methylation Process.4.19 Post-Translational Modifications- Ubiquitination Process.4.20 Post-Translational Modifications-SUMOylation Process.4.21 Post-Translational Modifications- Lipidation Process.4.22 Post-Translational Modifications- Proteolytic Cleavage Process.4.23 Post-Translational Modifications- Sulfation Process.4.24 Post-Translational Modifications- Nitrosylation Process.4.25 Post-Translational Modifications- Hydroxylation Process.4.26 Post-Translational Modifications- Carboxylation Process.Module 5: Regulation of Gene Expression.5.1 Introduction to Regulation of Gene Expression.5.2 Transcriptional Regulation.5.3 Post-Transcriptional Regulation.5.4 Translational Regulation.5.5 Post -Translational Regulation.5.6 Epigenetic Regulation.5.7 miRNA and lncRNA Regulation.Module 6: Genomic Technologies.6.1 Introduction to Genomic Technologies.6.2 Introduction to DNA Sequencing.6.3 Sanger Sequencing.6.4 Next Generation Sequencing.6.5 Applications of DNA Sequencing.Module 7: Genetic Engineering7.1 Introduction to Genetic Engineering.7.2 Historical Milestones in Genetic Engineering.7.3 Applications of Genetic Engineering7.4 Introduction to Recombinant DNA Technology.7.5 Key Components of Recombinant DNA Technology7.6 Applications of Recombinant DNA Technology7.7 DNA Cloning Process.7.8 Polymerase Chain Reaction (PCR).7.9 Gene Editing (CRISPR-Cas9).Part 2Assignments